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21c Museum Hotel Louisville

700 W Main St | Louisville, KY 40202-2634  [SEE MAP]Louisville, KY  [SEE ADDRESS]

Courtesy of 21c Museum Hotel Louisville

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Unique art concept in a convenient location
Some recent guests said rates are expensive for the market
With distinctive red plastic penguins and a modern design, this West Main Street hotel impresses recent guests with its atmosphere. There are plenty of avant-garde 21st-century art pieces to peruse in the lobby, meeting spaces and rooms. The chic accommodations, outfitted in a color scheme of white, gray and pale blue, feature free Wi-Fi access, flat-screen TVs and Nespresso coffee makers. Outside the rooms, travelers highlight the exemplary hospitality staff (led by swift room service) and the first-rate Proof on Main restaurant. Visitors should order the signature bison burger, washed down with one of Louisville's finest bourbons to get a taste of Kentucky's flavor. Thanks to its brand ties, the hotel participates in the Le Club AccorHotels program, where members can rack up points and redeem them for free nights.
Louisville, KY
Hotel Class
Property Type
Boutique hotel, 91 rooms
Primary View
City center, River
Modern, Historic



  • 4.5Hotel Class
  • GREATCritic Rating


U.S. News analyzed more than 30,000 hotels to find the best in the USA, Europe, Canada, Mexico, Bermuda and the Caribbean, based on reputation among travel experts, guest reviews and hotel class ratings.

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Critic Reviews

Other Awards

  • Condé Nast Readers' Choice List 2019

Condé Nast Traveler


The entire experience is Louisville at its finest—fresh and contemporary, with an anchor to its past.



When it opened in 2006, 21C immediately attracted national acclaim for its elegant restoration of a 19th-century building, attention to service, and cutting-edge art collection.

Fodor's Choice



This hotel offers contemporary art galore. View rotating selections of statues and paintings, many of which are meant to be provocative. Smartly appointed rooms have exposed brick walls and photo art.

AAA/CAA Four Diamond Awards 2019

Other Awards

  • Condé Nast Readers' Choice List 2019

Guest Reviews

A hotel's guest rating is calculated using data provided under license by Tripadvisor. A total of 1846 have reviewed the 21c Museum Hotel Louisville, giving it a rating of 4.5, on a scale of 1-5.

Tripadvisor Travel Rating: 

Tripadvisor Travel Rating: Tripadvisor Traveler Rating 4.5 based on 1846 reviews 4.5 (based on 1846 reviews)

Guest Rooms

Set within a group of 19th-century warehouses, the 21c Museum Hotel Louisville's modern guest rooms offer large windows, high ceilings and original artwork, with some rooms featuring exposed brick walls. All guest rooms include luxurious bedding, 42-inch flat-screen TVs and Nespresso coffee makers.
  • Bathrooms have Malin + Goetz products and plush robes

Standard room size320 square feet

  • Premium channels
  • Workspace/desk
  • Minifridge
  • Bathrobes/slippers
  • Minibar
  • Shower/tub combo
  • Separate shower
  • Separate tub
  • Internet
  • Wireless internet
  • Free internet
  • Fee for internet usage
  • Guest rooms with patios and balconies
  • Adjoining rooms available

Location & Parking

Situated in downtown Louisville, the 21c Museum Hotel Louisville combines contemporary art with boutique-style accommodations. The modern property offers rotating art exhibits and the Louisville Slugger Museum & Factory is less than a block away. There is an award-winning Southern bistro, Proof on Main, as well as a spa and meeting space. Given its design style, the property is best suited for adults.
  • Within walking distance of Evan Williams Bourbon Experience, KFC Yum! Center and the Riverwalk
  • 4 miles north of Churchill Downs and the Kentucky Derby Museum
  • 8 miles north of Louisville International Airport
  • 24-hour valet parking ($32)
  • 24-hour self-parking
  • Airport shuttle
  • Car service (with fee)

Within walking distance of:

  • Bus stop
  • Restaurants
  • Movie theater
  • Train station
  • Beach
  • Theater
  • Subway/metro stop
  • Grocery store
  • Shopping


21c Museum Hotel Louisville's Proof on Main offers a contemporary Southern bistro-style experience. The restaurant serves an array of dishes crafted from locally sourced ingredients, along with more than 120 of Kentucky’s best bourbons.
  • Rotating art exhibits within restaurant
  • Seasonal menus
  • In-room dining available from 6 a.m. to midnight on Sundays through Thursdays, and until 1 a.m. on Fridays and Saturdays

Number of restaurants1

Cuisine TypesAmerican

  • Fine dining
  • Casual dining
  • Quick service cafe/coffee shop/marketplace
  • Bar/lounge
  • Room service
  • 24-hour room service
  • free breakfast


The 21c Museum Hotel Louisville has an on-site spa available for guest use. The facility offers massage services, as well as a sauna and steam room.
  • In-room massage services available upon request
  • Advance reservations required for spa services

Services offered:

  • Massage
  • Facial
  • Body Treatments (i.e. scrubs, wraps)
  • Salon services
  • Outdoor treatment area
  • Steam room
  • Sauna


While the 21c Museum Hotel Louisville has an art focus and is designed to appeal to adults, the hotel does offer cribs for no additional charge and rollaways for $30 per night, as well as some child-friendly, in-room dining options. The hotel also offers a Kid's Exploration Package, which includes two tickets to the Kentucky Science Center and a tent for in-room camping.
    • Kids Club
    • Free Kids Club
    • Fee for Kids Club
    • Cribs
    • High Chairs


    There is a 24-hour on-site fitness center at the 21c Museum Hotel Louisville. The facility offers cardio machines and strength-training equipment.
      • Weight equipment
      • Cardio equipment
      • Yoga mats
      • Free fitness classes
      • Premium fitness classes (with fee)


      The 21c Museum Hotel Louisville has more than 9,000 square feet of art-filled event space for business meetings and gatherings. There is one conference room, four private meeting rooms and a large atrium that can host up to 450 people.
      • Catering provided by Proof on Main
      • On-site event team
      • Room blocks available

      Number of meeting rooms6

      • Business center
      • Meeting rooms
      • Meeting and event planners available


      The 21c Museum Hotel Louisville is a dog-friendly property. Advance notice is required, and guests must sign a pet waiver at check-in.
      • $75 nonrefundable pet cleaning fee
      • 50-pound weight limit
      • Pets allowed (with fee)
      • Dog walking
      • Pet-sitting


      The 21c Museum Hotel Louisville offers a modern art-filled setting for weddings. The property can host receptions for up to 250 guests, as well as rehearsal dinners, post-wedding brunches and bridal showers.
      • Customizable gourmet catering from Proof on Main
      • 21c art car limousine available
      • Pre-wedding massage services
      • Custom welcome gifts for guests can be arranged

      Maximum wedding guest capacity450

      • Hotel hosts weddings
      • Outdoor space for weddings
      • Wedding planners available

      Editor’s note: Hotel information is updated periodically. If this is your property and you notice any inaccuracies, please let us know. If you are interested in obtaining a badge to display on your website or in other media, please contact us.

      Find the Best Price

      at the 21c Museum Hotel Louisville

      Navigate forward to interact with the calendar and select a date. Press the question mark key to get the keyboard shortcuts for changing dates.

      Navigate backward to interact with the calendar and select a date. Press the question mark key to get the keyboard shortcuts for changing dates.

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