Once the home of Diego Colón, Christopher Columbus' son, this 16th-century viceregal palace (or residence of the governor/viceroy) was the nucleus of the Spanish court for more than 60 years. Inside, you'll find a museum housing an impressive collection of late medieval and Renaissance art. The house itself is also a work of art, featuring Moorish, Gothic and Renaissance touches.

Recent visitors praise this historic property, insisting that a tour of the Alcázar de Colón is a must for anyone who wants to learn more about the city's rich history. And be sure to pick up some headphones to take advantage of the museum's self-guided audio tours. Even though the headphone line can get a bit long on busier days, most travelers note doing this tour is well worth the wait.

Located along Calle Las Damas in the Zona Colonial, Alcázar de Colón is open Tuesday through Saturday from 9 a.m. to 5 p.m and on Sundays from 9 a.m. to 4 p.m. You'll have to pay 100 Dominican pesos (or $2.21 USD) to enter.